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The first crewed mission to the Moon in half a century blasted off from Florida on Wednesday.
The Artemis II's crew of four astronauts are currently working through a "pre-sleep" stage - but what exactly does this involve?
Dr Kevin Fong explains what life will be like for the crew on board.
He described how NASA has prepared for the challenges of living in space, including how the crew will sleep, exercise and maintain their physical and mental health.